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Table 3: Diagnostic predictive values for the differentiation of hemangioblastomas from metastases^{^a}
Reading Session and Statistic Observer 1 Observer 2
Conventional image set 
    AUC^{^b} 0.594 (0.400–0.768) 0.683 (0.489–0.840)
    Sensitivity (%) 18.8 (3/16) 43.7 (7/16)
    Specificity (%) 100 (14/14) 92.9 (13/14)
    Accuracy (%) 57 (17/30) 67 (20/30)
Combined ASL image set 
    AUC^{^b} 0.969 (0.831–0999) 1.000 (0.884–1.000)
    Sensitivity (%) 93.7 (15/16) 100 (16/16)
    Specificity (%) 100 (14/14) 100 (14/14)
    Accuracy (%) 97 (29/30) 100 (30/30)
P value for pair-wise comparison of ROC curves <.001 <.0001
P value calculated with the McNemar test for the comparison of accuracy <.001 .022
↵a Unless otherwise indicated, the numbers in parentheses are raw data. Sensitivity, specificity, and accuracy were calculated under the assumption that a confidence score of 4 or higher was considered positive for the diagnosis of hemangioblastoma.
↵b Data in parentheses are 95% CIs.