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Table 1: Cerebral blood flow values in patients and controls^{^a}
ROI Sections Voxels^{^b} CBF, Repeatability^{^c} CBF (Mean) (SD) (mL/100 g/min) P Value^{^d}
Patients Controls
Cerebellum 2 924 (144) 0.92 20.7 (9.3) 27.2 (7.0) .006
MFC 3 133 (30) 0.90 24.9 (5.6) 27.4 (5.1) .23
Lentiform nucleus 1 115 (15) 0.75 20.4 (2.7) 25.0 (4.0) <.001^{^e}
MTL 1 114 (15) 0.86 30.4 (5.6) 31.7 (3.8) .86
HCC 2 1350 (459) 0.72 22.5 (5.5) 21.6 (3.0) .47
Pons 3 68 (17) 0.90 22.0 (7.0) 24.1 (5.3) .19
SMA 2 130 (18) 0.72 25.1 (5.1) 25.2 (3.7) .93
Thalamus 2 116 (19) 0.92 26.8 (10.2) 34.1 (5.6) <.001^{^e}
Frontal WM 2 41 (8) 0.91 11.0 (5.0) 10.7 (2.2) .76
Lateral WM 2 136 (33) 0.89 12.2 (3.0) 13.8 (1.7) .014
Superior WM 2 67 (7) 0.88 14.2 (5.0) 12.6 (2.5) .17
Periventricular WM 1 186 (15) 0.88 8.0 (2.5) 13.1 (3.1) <.001^{^e}
Note:—HCC indicates high-convexity cortex; MFC, medial frontal cortex; MTL, medial temporal lobe; SMA, supplementary motor area.
↵a Data are mean with SD in parentheses unless otherwise indicated.
↵b Mean (SD) voxels in each ROI in patients.
↵c Repeatability of perfusion measurements between the 2 baseline investigations using the intraclass correlation coefficient.
↵d Unadjusted P values tested with the paired-samples t test.
↵e Significant after Holm-Bonferroni correction.