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Table 1: 
Clinical and radiographic exclusion criteria
Exclusion Criteria
Identified pathology in the brain
Prior intracranial operation
Motion or susceptibility artifacts causing image distortion of SyMRI
Known developmental delay in language or motor domains requiring therapy
Autism spectrum disorder
Fixed neurologic deficit related to intracranial disease
Spasticity with cerebral cause requiring therapy
Chronic epilepsy
Significant prematurity (younger than 34 weeks' GA at delivery)
Significant macrocephaly (head circumference >97th percentile)
Significant microcephaly (head circumference <3rd percentile)
Hydrocephalus
Head trauma with extra-axial hemorrhage
Genetic disorder known to involve brain development
Systemic steroid therapy within 1 mo of examination
  • Note:—GA indicates gestational age.