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Table 4: Tumor staging for HPV-related OPSCC^{^a}
T Category T Criteria
T0 No primary identified
T1 Tumor ≤2 cm in greatest dimension
T2 Tumor >2 but ≤4 cm in greatest dimension
T3 Tumor >4 cm in greatest dimension or extension to lingual surface of epiglottis
T4 Moderately advanced local disease; tumor invades the larynx, extrinsic muscles of tongue, medial pterygoid, hard palate or mandible, or beyond
↵a The T4a and T4b features from OPSCC staging in the seventh edition are now combined as T4 in the new eighth edition. Table adapted with permission of the American Joint Committee on Cancer, Chicago, Illinois. The original source for this material is the AJCC Cancer Staging Manual.¹

T Category	T Criteria
T0	No primary identified
T1	Tumor ≤2 cm in greatest dimension
T2	Tumor >2 but ≤4 cm in greatest dimension
T3	Tumor >4 cm in greatest dimension or extension to lingual surface of epiglottis
T4	Moderately advanced local disease; tumor invades the larynx, extrinsic muscles of tongue, medial pterygoid, hard palate or mandible, or beyond