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Summary of clinical documentation of CHARGE diagnosis for the 10 subjects according to the criteria set by Verloes⁸
Subject
1 2 3 4 5 6 7 8 9 10
Sex M M F F M M M M F F
Age at MRI (yr) 1 2 18 1 1 7 4 8 mo 1 19
Major criteria 
    Coloboma + + + + +
    Choanal atresia + + 
    SCC hypoplasia + + + + + + + + + +
Minor criteria 
    Rhombencephalic dysfunction +^1,2 +^1,2 +¹ +^1,2 +^1,2 +¹ +¹ +² +^1,2 
    Hypothalamohypophyseal dysfunction +³ +⁴ +⁴ +³ +⁴ +⁴ +⁴ 
    Malformation of ear +^5,6 +⁶ +⁶ +^5,6 +⁶ +⁶ +⁶ +⁶ +⁶ +⁶
    Malformation of mediastinum +⁷ +⁷ +⁷ +⁷ +⁷ +⁷ +^7,8 +⁷
    Mental retardation + + + + + 
    Typical CHARGE + + + + +
    Atypical CHARGE + + + + + 
Note:— + indicates present criteria; +¹, cochlear nerve hypoplastic or absent; +², brain stem hypoplasia; +³, undescended testes; +⁴, growth delay; +⁵, external ear malformation; +⁶, inner ear malformation; +⁷, cardiac malformation; +⁸, tracheoesophageal fistula.