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Table 3: Clinical nodal staging for NPC^{^a}
N Category N Criteria
Nx Regional lymph nodes cannot be assessed
N0 No regional lymph node metastasis
N1 Unilateral metastasis in cervical lymph node(s) and/or unilateral or bilateral metastasis in retropharyngeal lymph node(s) ≤6 cm in greatest dimension, above the caudal border of cricoid cartilage
N2 Bilateral metastasis in cervical lymph nodes ≤6 cm in greatest dimension, above the caudal border of cricoid cartilage
N3 Unilateral or bilateral metastasis in cervical lymph node(s) >6 cm in greatest dimension, and/or extension below the caudal border of cricoid cartilage
↵a Changes in the eighth edition reflect the designation of level IV or VB nodes as N3 disease with no distinct a or b status. Table adapted with permission of the American Joint Committee on Cancer, Chicago, Illinois. The original source for this material is the AJCC Cancer Staging Manual.¹