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Table 2: Median absolute BTB difference in longitudinal volume change for each deep GM structure for both hemispheres. Effect size, corresponding 95% confidence CI, and P values based on linear multilevel modelling are also presented
GM Structure Software Hemisphere Median Absolute Difference, μl 90th Percentile P Value Effect 95% CI Lower 95% CI Upper
Caudate nucleus FreeSurfer Left 71.80 219.88 .003 0.82 0.72 0.93
FIRST Left 85.84 442.31
FreeSurfer Right 74.20 253.22 .09 0.90 0.79 1.02
FIRST Right 87.26 264.69
Putamen FreeSurfer Left 117.00 315.58 <.001 0.73 0.64 0.84
FIRST Left 156.39 412.49
FreeSurfer Right 114.30 326.22 .003 0.77 0.64 0.91
FIRST Right 142.44 406.71
Amygdala FreeSurfer Left 63.50 173.60 <.001 0.76 0.66 0.87
FIRST Left 84.38 260.14
FreeSurfer Right 77.00 196.54 <.001 0.73 0.64 0.83
FIRST Right 101.25 331.70
Globus pallidus FreeSurfer Left 59.60 180.56 .75 1.03 0.87 1.22
FIRST Left 62.05 185.44
FreeSurfer Right 60.00 164.38 .48 0.96 0.85 1.08
FIRST Right 60.06 200.23
Thalamus FreeSurfer Left 100.90 315.08 .10 1.13 0.98 1.30
FIRST Left 91.76 262.30
FreeSurfer Right 88.20 243.46 <.001 0.78 0.69 0.89
FIRST Right 114.81 308.71