Table 3:

Median absolute BTB difference in longitudinal percentage volume change for each deep GM structure for both hemispheres. Effect size, corresponding 95% CI and P values based on linear multilevel modelling are also presented

GM Structure	Software	Hemisphere	Median Absolute Difference, %	90th Percentile	P Value	Effect	95% CI Lower	95% CI Upper
Caudate nucleus	FreeSurfer	Left	2.04	6.04	.002	0.09	0.02	0.41
	FIRST	Left	2.71	13.37	.002	0.09	0.02	0.41
	FreeSurfer	Right	2.08	6.92	.004	0.16	0.05	0.55
	FIRST	Right	2.63	8.15	.004	0.16	0.05	0.55
Putamen^{^a}	FreeSurfer	Left	2.48	6.87	<.001	0.07	0.02	0.29
	FIRST	Left	3.43	9.51	<.001	0.07	0.02	0.29
	FreeSurfer	Right	2.46	6.77	NA	NA	NA	NA
	FIRST	Right	3.32	9.48	NA	NA	NA	NA
Amygdala^{^a}	FreeSurfer	Left	6.14	17.64	.02	0.07	0.01	0.69
	FIRST	Left	6.60	21.29	.02	0.07	0.01	0.69
	FreeSurfer	Right	6.24	16.52	NA	NA	NA	NA
	FIRST	Right	8.63	28.95	NA	NA	NA	NA
Globus pallidus	FreeSurfer	Left	4.32	13.04	.49	1.63	0.40	6.63
	FIRST	Left	3.65	10.92	.49	1.63	0.40	6.63
	FreeSurfer	Right	4.30	12.22	.94	0.95	0.29	3.17
	FIRST	Right	3.54	11.75	.94	0.95	0.29	3.17
Thalamus	FreeSurfer	Left	1.52	4.61	.33	0.62	0.23	1.64
	FIRST	Left	1.26	3.53	.33	0.62	0.23	1.64
	FreeSurfer	Right	1.41	3.82	.05	0.33	0.11	1.01
	FIRST	Right	1.59	4.31	.05	0.33	0.11	1.01

Note:—NA indicates not available.
↵a For the right amygdala and putamen, results are not presented because of lack of validity caused by failures in the model fit.