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Table 4: MRI features among telomere maintenance glioblastoma subtypes
MRI Feature Telomere Maintenance Subtype
ALT+/M− ALT−/M− ALT−/M+ Pearson χ² and P Values^{^a} ALT+/M+
No. of patients 26 92 56 6
Regular margin, % (no.) 58 (15) 30 (28) 30 (17) 7.3, .026 33 (2)
Fungating margin, % (no.) 19 (5) 53 (49) 61 (34) 12.8, .002 67 (4)
Cystic component, % (no.) 39 (10) 24 (22) 11 (6) 8.5, .014 50 (3)
Radiologic necrosis, % (no.) 58 (15) 73 (67) 86 (48) 7.7, .021 83 (5)
Extensive PTE, % (no.) 23 (6) 23 (21) 45 (25) 8.6, .014 17 (1)
Multifocal lesion, % (no.) 15 (4) 12 (11) 23 (13) NS 33 (2)
Hemorrhage, % (no.) 8 (2) 20 (18) 7 (4) NS 3 (2)
Note:—NS indicates not significant.
↵a Statistical comparisons were made between 3 groups: ALT+/M−, ALT−/M−, and ALT−/M+.

MRI Feature	Telomere Maintenance Subtype
MRI Feature	ALT+/M−	ALT−/M−	ALT−/M+	Pearson χ² and P Values^{^a}	ALT+/M+
No. of patients	26	92	56		6
Regular margin, % (no.)	58 (15)	30 (28)	30 (17)	7.3, .026	33 (2)
Fungating margin, % (no.)	19 (5)	53 (49)	61 (34)	12.8, .002	67 (4)
Cystic component, % (no.)	39 (10)	24 (22)	11 (6)	8.5, .014	50 (3)
Radiologic necrosis, % (no.)	58 (15)	73 (67)	86 (48)	7.7, .021	83 (5)
Extensive PTE, % (no.)	23 (6)	23 (21)	45 (25)	8.6, .014	17 (1)
Multifocal lesion, % (no.)	15 (4)	12 (11)	23 (13)	NS	33 (2)
Hemorrhage, % (no.)	8 (2)	20 (18)	7 (4)	NS	3 (2)