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Prevalence of MRI findings in children with achondroplasia
MRI FindingPrevalence
Deep transverse temporal sulcus (axial T1WI)13/13 (100%)
Sagittal clefting in the medial temporal lobe (sagittal T2WI)13/13 (100%)
Incomplete hippocampal inversion12/13 (92%)
Ventriculomegaly12/13 (92%)
Oversulcation of the mesial temporal lobe11/13 (85%)
Extension of oversulcation to the calcar avis9/13 (69%)
Loss of gray-white matter differentiation of the mesial temporal lobe5/7a (71%)
Abnormal triangular shape of the temporal horn6/13 (46%)
Megalencephaly5/13 (38%)
Temporal lobe enlargement1/13 (8%)
  • ↵a In the 6 children younger than 36 months of age, loss of gray-white matter differentiation of the mesial temporal lobe could not be accurately assessed on available sequences due to the incomplete myelination.