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Table 2: Diagnostic performance of MR imaging for the discrimination of early NPC from BH
Volume Size Asymmetry Signal Asymmetry Deep Mucosal White Line Adenoid Test positive for NPC Volume ≥ 5.01 cm3 %ΔA ≥ 33.7% Signal asymmetry present Focal loss of the deep mucosal white line Septa absent or distorted (excluding septa distorted by cysts) n = 333 (NPC = 189, BH = 144) n = 333 (NPC = 189, BH = 144) n = 333 (NPC = 189, BH = 144) n = 253 (NPC = 180, BH2 = 73) n = 172 (NPC = 111, BH2 = 61) Area under the curve (95% CI) 0.676 (0.618–0.734) 0.948 (0.926–0.971) P value <.001 <.001 True-positive (No.) 119 167 161 153 111 False-positive (No.) 47 13 26 10 9 True-negative (No.) 97 131 118 63 52 False-negative (No.) 70 22 28 27 0 Sensitivity (%) 63.0 88.4 85.2 85.0 100.0 Specificity (%) 67.4 91.0 81.9 86.3 85.2 Positive predictive value (%) 71.7 92.8 86.1 93.9 92.5 Negative predictive value (%) 58.1 85.6 80.8 70.0 100.0 Accuracy (%) 64.9 89.5 83.8 85.4 94.8