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Table 2: Longitudinal DTI changes in chronic lesional tissue
Change/Month 95% CI % Annualized Change P Value
All T2 lesions 
    RD × 10⁻⁶ mm²/s 0.05683 −0.181 to 0.295 0.11% .6401
    AD × 10⁻⁶ mm²/s 0.5411 0.251 to 0.831 0.62% .0003^{^a}
    FA × 10⁻³ 0.163 0.001 to 0.324 0.61% .0482^{^a}
    MD ×10⁻⁶ mm²/s 0.2695 0.040 to 0.499 0.41% .0211^{^a}
BH 
    RD × 10⁻⁶ mm²/s 0.3392 −0.028 to 0.706 0.57% .0701
    AD × 10⁻⁶ mm²/s 0.1967 −0.200 to 0.593 0.22% .331
    FA × 10⁻³ −0.2137 −0.422 to −0.005 −0.91% .0444
    MD × 10⁻⁶ mm²/s 0.2919 −0.059 to 0.643 0.42% .1026
NBH 
    RD ×10⁻⁶ mm²/s −0.4137 −0.967 to 0.140 −0.85% .1432
    AD × 10⁻⁶ mm²/s −0.2392 −0.838 to 0.360 −0.28% .434
    FA × 10⁻³ 0.2907 −0.025 to 0.606 0.99% .0708
    MD × 10⁻⁶ mm²/s −0.355 −0.174 to 0.884 −0.58% .1883
↵a P < .05.