Table 2:

Diagnostic performance of morphologic MRI alone, quantitative DWI alone, qualitative DWIMRI, and quantitative DWIMRI with ADCmean < 1.22 × 10⁻³ mm²/s

	Morphologic MRI	Quantitative DWI with ADCmean < 1.22	Morphologic MRI with Qualitative DWI	Morphologic MRI with Quantitative DWI (ADCmean < 1.22)
TP (No.)	30	30	34	35
TN (No.)	52	56	59	62
FP (No.)	13	9	6	3
FN (No.)	8	8	4	3
Sensitivity (%)^{^a}	78.9	78.9	89.4	92.1
(95% CI)	(65.9–91.9)	(65.9–91.9)	(79.7–99.2)	(83.5–100.0)
Specificity (%)^{^b}	80.0	86.1	90.8	95.4
(95% CI)	(70.3–89.7)	(74.8–93.1)	(83.7–97.8)	(90.3–100.0)
PPV (%)	69.7	76.9	85.0	92.1
(95% CI)	(56.1–83.5)	(60.3–88.3)	(73.9–96.1)	(83.5–100.0)
NPV (%)	86.6	87.5	93.6	95.4
(95% CI)	(78.1–95.3)	(76.3–94.1)	(87.6–99.6)	(90.2–100.0)
LR+^{^c}	3.94	5.70	9.69	19.9
(95% CI)	(2.36–6.59)	(3.04–10.68)	(4.48–20.9)	(6.58–60.5)
LR−^{^d}	0.26	0.24	0.11	0.08
(95% CI)	(0.14–0.49)	(0.13–0.45)	(0.04–0.29)	(0.03–0.24)

Note:—TP indicates true-positive; TN, true-negative; FP, false-positive; FN, false-negative; PPV, positive predictive value; NPV, negative predictive value.
↵a Comparison of sensitivities: MRI vs DWI: P = 1; MRI vs qualitative DWIMRI: P = .10; MRI vs quantitative DWIMRI: P = .025; qualitative DWIMRI vs quantitative DWIMRI: P = .31; DWI vs quantitative DWIMRI: P = .05.
↵b Comparison of specificities: MRI vs DWI: P = .34; MRI vs qualitative DWIMRI: P = .05; MRI vs quantitative DWIMRI: P = .004; qualitative DWIMRI vs quantitative DWIMRI: P = .18; DWI vs quantitative DWIMRI: P = .03.
↵c Comparison of LR+: MRI vs DWI: P = .36; MRI vs qualitative DWIMRI: P = .03; MRI vs quantitative DWIMRI: P = .004; qualitative DWIMRI vs quantitative DWIMRI: P = .17; DWI vs quantitative DWIMRI: P = .02.
↵d Comparison of LR−: MRI vs DWI: P = .85; MRI vs qualitative DWIMRI: P = .06; MRI vs quantitative DWIMRI: P = .01; qualitative DWIMRI vs quantitative DWIMRI: P = .24; DWI vs quantitative DWIMRI: P = .04.