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Table 5: Correlations between quantitative imaging measures in the subcortical GM structures and global imaging variables in patients with MS^{^a}
Basal Ganglia Variable Global Imaging Variable
MPF in NAWM MPF in GM MPF in Lesions Lesion Volume
MPF (CN) 0.54^{^b} 0.43^{^c} 0.05 −0.36
MPF (GP) 0.63^{^b} 0.59^{^b} 0.52^{^b} −0.30
MPF (putamen) 0.56^{^b} 0.51^{^b} 0.32 −0.37^{^c}
MPF (SN) 0.63^{^b} 0.50^{^b} 0.45^{^c} −0.31
MPF (thalamus) 0.55^{^b} 0.39^{^c} 0.19 −0.24
T2* (CN) 0.01 0.14 0.08 0.09
T2* (GP) 0.05 0.29 0.15 −0.04
T2* (putamen) 0.19 0.30 0.14 0.02
T2* (SN) −0.28 −0.12 −0.08 0.11
T2* (thalamus) −0.07 0.02 0.16 0.13
↵a Data are Pearson correlation coefficients. To correct for deviations from normal distribution, we applied the Box-Cox transformation to the lesion volume with the power of 0.5.
↵b P < .01.
↵c .01 ≤ P < .05.