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Table 2:

Spinal MRI findings in AQP4 antibody–positive and –negative groupsa

Imaging FeaturesAQP4 Antibody–Positive Group (n = 15)AQP4 Antibody–Negative Group (n = 26)
Cervicomedullary junction involvement9 (60%)6 (23%)
    Medulla oblongata involvement4 (27%)1 (4%)
Cord expansion ratio (mean) (onset ≤2 months)b1.35 ± 0.151.24 ± 0.15
Cord expansion ratio (mean) (onset ≤15 days)c1.34 ± 0.171.24 ± 0.17
Bright spotty lesion
    Negative1 (7%)18 (69%)
    Positive14 (93%)8 (31%)
Involved segment
    Cervical5 (33%)7 (27%)
    Cervicothoracic8 (53%)5 (19%)
    Thoracic2 (13%)10 (38%)
    Thoracolumbar0 (0%)1 (4%)
    Holocord0 (0%)3 (12%)
No. of segments involved (mean)9 ± 47 ± 4
Axial distribution
    Central10 (67%)21 (81%)
    Peripheral4 (27%)4 (15%)
    Both1 (7%)1 (4%)
>Half of the cord area12 (80%)24 (92%)
Enhancement
    No enhancement4 (27%)6 (23%)
    <50% enhancement9 (60%)17 (65%)
    >50% enhancement0 (0%)0 (0%)
    Not available2 (13%)3 (12%)
  • a Data are number and percentage unless otherwise indicated.

  • b Cord expansion ratio was measured only for 32 patients.

  • c Cord expansion ratio was measured only for 22 patients.