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Table 2: Pair-wise comparison of ROC curves
Reader, Diagnostic Instrument ΔAUC SE 95% CI z P
Reader 1 
    sMRI vs sMRI + MRA 0.156 0.046 0.066–0.247 3.381 <.01
    sMRI vs sMRI + MRA + pCASL 0.174 0.047 0.082–0.266 3.701 <.01
    sMRI + MRA vs sMRI+MRA + pCASL 0.018 0.028 −0.036–0.072 0.644 .52
Reader 2 
    sMRI vs sMRI + MRA 0.112 0.044 0.027–0.197 2.581 <.01
    sMRI vs sMRI + MRA + pCASL 0.193 0.043 0.108–0.277 4.475 <.01
    sMRI + MRA vs sMRI + MRA + pCASL 0.081 0.030 0.022–0.140 2.675 <.01
Pooled Readers 1 + 2 
    sMRI vs sMRI + MRA 0.136 0.042 0.053–0.219 3.208 <.01
    sMRI vs sMRI + MRA + pCASL 0.179 0.045 0.091–0.267 3.965 <.01
    sMRI + MRA vs sMRI + MRA + pCASL 0.043 0.027 −0.009–0.100 1.615 .11

Reader, Diagnostic Instrument	ΔAUC	SE	95% CI	z	P
Reader 1
sMRI vs sMRI + MRA	0.156	0.046	0.066–0.247	3.381	<.01
sMRI vs sMRI + MRA + pCASL	0.174	0.047	0.082–0.266	3.701	<.01
sMRI + MRA vs sMRI+MRA + pCASL	0.018	0.028	−0.036–0.072	0.644	.52
Reader 2
sMRI vs sMRI + MRA	0.112	0.044	0.027–0.197	2.581	<.01
sMRI vs sMRI + MRA + pCASL	0.193	0.043	0.108–0.277	4.475	<.01
sMRI + MRA vs sMRI + MRA + pCASL	0.081	0.030	0.022–0.140	2.675	<.01
Pooled Readers 1 + 2
sMRI vs sMRI + MRA	0.136	0.042	0.053–0.219	3.208	<.01
sMRI vs sMRI + MRA + pCASL	0.179	0.045	0.091–0.267	3.965	<.01
sMRI + MRA vs sMRI + MRA + pCASL	0.043	0.027	−0.009–0.100	1.615	.11