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Table 2: AUC from the ROC for individual and combined classifiers and decision thresholds, to discriminate brain tumors
AUC P Value Thresholds Sensitivity Specificity
PCNSL vs GBM, metastases
    PSR_max 0.940 <.001^{^a} ≥87.00 82.1 100.0
    Cho/NAA 0.835 <.001^{^a} ≤2.07 73.9 100.0
    rCBV 0.789 <.001^{^a} ≤2.59 92.9 63.0
    Lac/Cr 0.728 .006^{^a} ≥0.87 87.0 56.5
    Cho/Cr 0.665 .01^{^a} ≥2.84 56.5 77.8
    Lip/Cr 0.638 .32 
    PSR_max–Cho/NAA 0.988 <.001^{^a} 95.7 100.0
GBM vs PCNSL, metastases 
    rCBV 0.911 <.001^{^a} ≥2.86 85.7 92.7
    Cho/NAA 0.835 <.001^{^a} ≥2.57 100.0 73.9
    Lac/Cr 0.710 .40 
    Cho/Cr 0.648 .68 
    PSR_max 0.633 .18 
    Lip/Cr 0.629 .19 
    rCBV–Cho/NAA 0.960 <.001^{^a} 85.7 100.0
Metastases vs PCNSL, GBM 
    PSR_max 0.969 <.001^{^a} ≤75.00 100.0 83.3
    Lac/Cr 0.957 <.001^{^a} ≤0.95 100.0 81.8
    Cho/Cr 0.868 <.001^{^a} ≤1.80 92.3 81.1
    Lip/Cr 0.813 .02^{^a} ≥2.90 100.0 64.9
    rCBV 0.532 .51 
    PSR_max–Lac/Cr 0.988 <.001^{^a} 100.00 97.0
    PSR_max–Cho/Cr 1.000 <.001^{^a} 100.00 100.0
↵a Significant.