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Table 2: Neuroimaging findings
Imaging Findings No. % Imaging Findings No. %
White matter abnormalities 16/16 100 Atrophy 15/16 94
Symmetry Atrophy predominance 
    Symmetric 10/16 63     Frontal 6/15 40
    Asymmetric 6/16 37     Frontoparietal 8/15 53
Confluence of lesions     Parietal 1/15 7
    Confluent 10/16 63 Corpus callosum involvement 
    Patchy 6/16 37     Hyperintensities 13/16 81
White matter abnormalities predominance     Atrophy 14/16 88
    Frontal 13/16 81 Corticospinal tract
Deep gray matter nuclei 10/16
2/16 63
13
    Frontoparietal 3/16 19 External capsule 7/16 44
Lobar distribution Posterior fossa 6/16 37
    Frontal 16/16 100 Enlarged perivascular spaces 4/16 25
    Parietal 16/16 100 Diffusion-weighted imaging 
    Temporal 11/16 69     Hyperintensities 6/8 75
    Occipital 8/16 50     Restricted ADC 4/6 67
U-fiber involvement 8/16 50 Calcifications 
White matter rarefaction 0/16 0     T2* 0/8 0
    CT 4/6 67
Gadolinium enhancement 0/6 0
Cavum septum pellucidum 8/16 50