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Table 1: Baseline characteristics of patients and tumors
Total (n = 59) HPV+ (n = 28) HPV− (n = 31) P Value
Age (yr) 64.9 64.4 65.4 .904
Sex 
    Male 43 19 24 .413
    Female 16 9 7 
Smoker 34/59 8/28 26/31 <.0001
Site 38, Palatine tonsil 20, Palatine tonsil 18, Palatine tonsil .611
17, Tongue base 7, Tongue base 10, Tongue base 
3, Soft palate 1, Soft palate 2, Soft palate 
1, Posterior wall 1, Posterior wall 
TNM classification 
    T T2 = 25 T2 = 16 T2 = 9 .084
T3 = 2 T3 = 1 T3 = 1 
T4 = 32 T4 = 11 T4 = 21 (16, T4a; 5, T4b) 
    N N0 = 14 N0 = 7 N0 = 7 .002
N1 = 15 N1 = 13 N1 = 2 
N2 = 18 N2 = 6 N2 = 12 (8, N2b; 4, N2c) 
N3 = 12 N3 = 2 N3 = 10 (N3b = 10) 
    M M0 = 57 M0 = 27 M0 = 30 .144
M1 = 2 M1 = 1 M1 = 1 
Note:—HPV+ indicates human papillomavirus-positive; HPV−, human papillomavirus-negative.

	Total (n = 59)	HPV+ (n = 28)	HPV− (n = 31)	P Value
Age (yr)	64.9	64.4	65.4	.904
Sex
Male	43	19	24	.413
Female	16	9	7
Smoker	34/59	8/28	26/31	<.0001
Site	38, Palatine tonsil	20, Palatine tonsil	18, Palatine tonsil	.611
	17, Tongue base	7, Tongue base	10, Tongue base
	3, Soft palate	1, Soft palate	2, Soft palate
	1, Posterior wall		1, Posterior wall
TNM classification
T	T2 = 25	T2 = 16	T2 = 9	.084
	T3 = 2	T3 = 1	T3 = 1
	T4 = 32	T4 = 11	T4 = 21 (16, T4a; 5, T4b)
N	N0 = 14	N0 = 7	N0 = 7	.002
	N1 = 15	N1 = 13	N1 = 2
	N2 = 18	N2 = 6	N2 = 12 (8, N2b; 4, N2c)
	N3 = 12	N3 = 2	N3 = 10 (N3b = 10)
M	M0 = 57	M0 = 27	M0 = 30	.144
	M1 = 2	M1 = 1	M1 = 1