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Table 4: Pre- and postinitiation of chronic transfusion therapy ASL perfusion changes^{^a}
Pt Pretransfusion Posttransfusion P Value
MCA (R) MCA (L) ACA (R) ACA (L) PCA (R) PCA (L) Avg MCA (R) MCA (L) ACA (R) ACA (L) PCA (R) PCA (L) Avg
1 96 NA 78 NA 93 NA 89 95 NA 94 NA 87 NA 92 .69
2 79 71 64 65 62 73 69 NA 87 NA 84 NA 80 84 .06
3 103 91 102 98 111 107 102 75 78 76 76 73 75 76 <.001^{^b}
4 NA 89 NA 80 NA 80 83 NA 75 NA 82 NA 76 78 .37
5 90 96 81 93 82 88 88 93 96 95 101 91 93 95 .02^{^c}
6 84 102 88 100 78 83 90 79 96 81 86 78 76 83 .02^{^b}
7 98 93 88 90 92 88 92 81 84 74 85 74 83 81 .005^{^b}
8 70 68 70 65 65 64 67 74 79 64 71 60 60 68 .74
9 70 70 64 66 63 71 67 69 74 77 85 73 80 87 .02^{^c}
T 86 78 79 82 81 82 81 81 84 80 80 77 78 80 .47
Note:—Pt indicates patient; R, right; L, left; Avg, average/mean whole-brain CBF; NA, not applicable/excluded; T, mean of each arterial territory.
↵a Arterial territory–specific and mean whole-brain CBF values (in milliliters/100 g of tissue/min) from 9 patients with transfusion prior to (left columns) and at the first scan after (right columns) transfusion initiation. In the interest in space and simplicity, CBF values were rounded to the nearest whole number for this display.
↵b Significant.
↵c Significant increase in mean whole-brain CBF.