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Table 2: Observed R1 enhancement of the pixels of the ROI line drawn by a neuroradiologist to encapsulate the enhancing tumor, as a percentage of all values above dR1 = 0.2 seconds−1, the mean dR1, and the mean dR1 of all values of >0.2 seconds−1a
dR1 >0.2 s−1 (%) Mean dR1 (s−1) Mean dR1 (>0.2 s−1 only) (s−1) Synthetic Subtraction Synthetic Subtraction Synthetic Subtraction On ROI line 35.8 ± 14.3 50.3 ± 10.2 0.19 ± 0.09 0.27 ± 0.08 0.48 ± 0.12 0.46 ± 0.11 + 1 mm 8.0 ± 5.8 17.4 ± 9.0 0.03 ± 0.02 0.08 ± 0.05 0.35 ± 0.08 0.37 ± 0.12 + 2 mm 2.3 ± 1.5 8.6 ± 4.9 0.01 ± 0.01 0.04 ± 0.04 0.32 ± 0.15 0.37 ± 0.17
a Results are listed for the R1 difference generated by synthesizing the R1 difference map and subtraction of the pre- and post-GBCA R1 maps. Two more ROI lines were created at 1- and 2-mm outward to analyze the results if a larger margin around the enhancing tumor had been drawn.