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Table 2: Comparison between CCT images alone and CCT-plus-BSI images of skull base invasion^{^a}
Parameter TP^{^b} TN^{^b} FN^{^b} FP^{^b} Sensitivity (%) P Value Specificity (%) P Value PPV (%) NPV (%)
All sites 
    CCT alone 66 155 18 25 79 (68–87) .016^{^c} 86 (80–90) .010^{^c} 73 90
    CCT-plus-BSI 78 172 6 8 93 (85–97) 96 (91–98) 91 97
Sphenoid body 
    CCT alone 18 14 4 8 82 (60–95) .625 64 (41–83) .039^{^d} 69 78
    CCT-plus-BSI 20 21 2 1 91 (71–99) 95 (77–100) 95 91
Clivus 
    CCT alone 11 22 9 2 55 (32–77) .031^{^d} 92 (73–99) 1.000 85 71
    CCT-plus-BSI 17 22 3 2 85 (62–97) 92 (73–99) 89 88
Base of the pterygoid process 
    CCT alone 17 60 1 10 94 (73–100) .157 86 (75–93) .012^{^c} 63 98
    CCT-plus-BSI 18 68 0 2 100 (81–100) 97 (90–100) 90 100
Petrous apex 
    CCT alone 20 59 4 5 83 (63–95) .221 92 (83–97) .306 80 94
    CCT-plus-BSI 23 61 1 3 96 (79–100) 95 (87–99) 88 98
Note:—FN indicates false-negative findings; FP, false-positive findings; NPV, negative predictive value; PPV, positive predictive value; TN, true-negative findings; TP, true-positive findings.
↵a Numbers in parentheses are 95% confidence intervals.
↵b Data are numbers of findings.
↵c P < .05, according to the generalized estimating equations that accounted for the multiple observations within patients.
↵d P < .05, as determined with the McNemar test.