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Conventional and advanced MRI features useful for differentiating between nCET and edema
nCETEdema
Conventional MRI features
    Gray matter involvementSpares the gray matter
    EccentricRelatively concentric around enhancing lesions
    Relatively mild FLAIR and T2 hyperintensityMore marked FLAIR and T2 hyperintensity
    Focal parenchymal expansionMore diffuse mass effect if marked edema
Advanced MRI sequences
    Relative diffusion restrictionFacilitated diffusion
    Choline elevation, NAA depletionNormal MRS findings
    Elevated rCBV around CETrCBV elevation confined to CET
  • Note:—rCBV indicates relative cerebral blood volume.