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Clinical outcomes after subarachnoid hemorrhage: comparison between the antiplatelet and the control groups
Outcomes Antiplatelet Group vs Control Group (95% CI) (I²) No. of Articles P Value
Overall rate of delayed cerebral ischemia 219/1060 vs 485/1762, OR = 0.781 (95% CI, 0.46–1.31) (I² = 76.9%) 7 .33
Delayed cerebral ischemia endovascular group 157/778 vs 413/1410, OR = 0.552 (95% CI, 0.273–1.115) (I² = 80.1%) 4 .06^{^a}
Delayed cerebral ischemia surgical group 42/195 vs 61/278, OR = 0.952 (95% CI, 0.288–3.147) (I² = 79.5%) 3 .5
Delayed cerebral ischemia long-term AT^{^b} 63/438 vs 96/353, OR = 0.379 (95% CI, 0.12–1.2) (I² = 68%) 3 .06^{^a}
Delayed cerebral ischemia short-term AT^{^c} 148/559 vs 349/1265, OR = 1.35 (95% CI, 0.81–2.23) (I² = 80.1%) 4 .5
Cerebral vasospasm 79/414 vs 84/327, OR = 0.52 (95% CI, 0.2–1.5) (I² = 83%) 2 .2
Good outcome 803/1144 vs 1175/1775, OR = 1.368 (95% CI, 1.117–1.676) (I² = 9.3%) 8 .002^{^a}
Mortality 79/672 vs 97/571, OR = 0.656 (95% CI, 0.47–0.91) (I² = 0%) 5 .01^{^a}
Overall rate of complications 40/438 vs 28/353, OR = 1.01 (95% CI, 0.34–3.01) (I² = 42%) 3 .9
Overall rate of hemorrhagic complications 32/438 vs 15/353, OR = 1.7 (95% CI, 0.89–3.38) (I² = 1%) 3 .1
Overall rate of major hemorrhagic events 8/438 vs 8/353, OR = 0.857 (95% CI, 0.32–2.28) (I² = 10) 3 .7
↵a Significant.
↵b Long-term AT = AT for 3 or 4 weeks.
↵c Short-term AT = AT for <2 weeks.