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Table 1: Comparison of baseline demographics, presentations, procedural efficacy, and safety between the GUARD and standard thrombectomy techniques
GUARD (n = 45) Standard (n = 45) P Value
Sex (% male) 42 51 .53
Median age (range/yr) 69 (21–92) 74 (39–92) .09
Median NIHSS score (range) 17 (6–30) 17 (5–32) .68
Median CT ASPECTS (range) 9 (6–10) 9 (6–10) .89
CTP (%) 44 56 .40
IV rtPA (%) 36 49 .29
Vessel occlusion (%) .88
    ICA terminus 25 22 
    Cervical ICA + MCA 4 7 
    MCA (M1–M2) 71 71 
Risk factors (%) 
    AF 44 53 .53
    HTN 76 80 .80
    DM 20 27 .62
    Smoker 9 9 .99
    HLD 49 49 .99
    Previous stroke/TIA 7 11 .71
Median symptom onset-to-groin puncture time (range/min) 192 (78–1193) 219 (27–1097) .241
Median symptom onset to reperfusion time (range/min) 254 (107–1245) 279 (108–1226) .21
Median groin puncture to reperfusion time (range/min) 52 (29–225) 61 (23–184) .20
Mean No. of passes ± SD 2.3 ± 1.3 2.8 ± 1.5 .09
First-pass reperfusion (%) 39 23 .17
Final mTICI score (%) .046^{^a}
    3 51 40 
    2c 16 7 
    2b 31 33 
    2a 2 16 
    1 0 2 
    0 0 2 
Successful reperfusion mTICI ≥ 2b (%) 98 80 .015^{^a}
Complete reperfusion mTICI 2c/3 (%) 67 47 .09
mTICI 3 (%) 51 40 .40
Adjunctive stenting/angioplasty (%) 20 11 .26
SICH (%) 2 9 .36
Neurovascular complications (%) 4 9 .68
Median mRS at 90 days (range) 2 (0–6) 4 (0–6) .01^{^a}
mRS ≤ 2 at 90 days (%) 67 43 .04^{^a}
Mortality at 90 days (%) 13 30 .10
Note:—AF indicates atrial fibrillation; HTN, hypertension; DM, diabetes mellitus; HLD, hyperlipidemia.
↵a Significant.