1naresh2naresh
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TE (n = 17) Tumor (n = 30) Total (n = 47) Age (yr) Mean (SD) 56 (10) 55 (13) 55 (12) Range 38-77 20-80 20-80 Sex Male 11 (65%) 18 (60%) 29 (62%) Female 6 (35%) 12 (40%) 18 (38%) Interval time between end or radiation therapy and surgery (mo) Median (range) 11.4 (0.6-60.4) 10.7 (1.3-101.5) 10.9 (0.6-101.5) Bevacizumab at time of surgeryb 2 (12%) 3 (10%) 5 (11%) Surgical procedure Biopsy 3 (18%) 4 (13%) 7 (15%) >90% resection 3 (18%) 9 (30%) 12 (25%) Gross total resection 11 (64%) 17 (57%) 28 (60%) HGG histopathology Anaplastic astrocytoma, WHO grade III 2 (12%) 0 2 (4%) Glioblastoma, WHO grade IV 15 (88%) 29 (97%) 44 (94%) Gliosarcoma, WHO grade IV 0 1 (3%) 1 (2%) HGG molecular features IDH wild type 11 (65%) 11 (37%) 22 (47%) IDH mutant 0 2 (7%) 2 (4%) Unknown IDH status 6 (35%) 17 (56%) 23 (49%) MGMT-unmethylated 6 (35%) 15 (50%) 21 (45%) MGMT-methylated 6 (35%) 8 (27%) 14 (30%) Unknown MGMT status 5 (30%) 7 (23%) 12 (25%)
Note:—IDH indicates isocitrate dehydrogenase; MGMT, O-6-methylguanine-DNA methyltransferase; WHO, World Health Organization.
↵a Percentage values in parentheses for sex, bevacizumab at time of the operation, surgical procedure, HGG histopathology, and HGG molecular features are percentages relative to the number of patients in each column.
↵b Patient received a dose of bevacizumab within 1 month of the surgical procedure for suspected recurrence.