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Table 2:

MR imaging characteristics of multinodular and vacuolating posterior fossa lesions of unknown significance (MV-PLUS) at diagnosis and during follow-up

No. of PatientsPercentage (%)
Location
    Center of the lesion
        Cerebellum
            Vermis7/1164
            Left cerebellar hemisphere1/119
            Right cerebellar hemisphere2/1118
            Left cerebellar peduncle1/119
            Right cerebellar peduncle0/110
        Brain stem0/110
    All areas involved
        Cerebellum
            Vermis7/1164
            Left cerebellar hemisphere3/1127
            Right cerebellar hemisphere8/1173
            Left cerebellar peduncle1/119
            Right cerebellar peduncle0/110
        Brain stem0/110
Overall size (median) (IQR) (mm)27 (24)
Size of the nodules (median) (IQR) (mm)4 (5)
DWI
    Restriction0/110
T2* or SWI
    Presence of ITSS0/110
    Blooming0/110
PWI
    rCBV (median) (IQR)0.62 (0.06)
    rCBF (median) (IQR)0.61 (0.06)
MRS
    TE = 35 ms
        Choline/creatine (median) (IQR)0.9 (0.2)
        Choline/N-acetyl aspartate (median) (IQR)0.9 (0.1)
        N-acetyl aspartate/creatine (median) (IQR)1 (0.2)
    TE = 135 ms
        Choline/creatine (median) (IQR)1.2 (0)
        Choline/N-acetyl aspartate (median) (IQR)1 (0)
        N-acetyl aspartate/creatine (median) (IQR)1.2 (0)
Type of margins
    Sharp11/11100
    Blurred0/110
Mass effect
    Yes4/1136
    No7/1164
Associated imaging abnormalities
    None7/1164
    Small-vessel disease3/1127
    Colloid cyst1/119
    Cholesteatoma1/119
  • Note:—ITSS indicates intratumoral susceptibility signal; rCBV, relative CBV; rCBF, relative CBF.