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Table 2: Ketone body concentrations as measured by MR spectroscopy before and after treatment with a ketogenic diet in both the lesion and contralateral brain^{^a}
Baseline (IU) No. Week 8 (IU) No. P Value
Ace 
    Contralateral brain 0.04 ± 0.01 5 0.16 ± 0.04 9 .004^{^b}
    Lesion 0.06 ± 0.03 4 0.27 ± 0.06 9 .005^{^b}
bHB 
    Contralateral brain 0.09 ± 0.06 2 0.28 ± 0.08 6 .12
    Lesion 0.07 ± 0.07 1 0.79 ± 0.32 5 .046^{^c}
AcAc 
    Contralateral brain 0.07 ± 0.04 3 0.06 ± 0.03 3 .76
    Lesion 0.03 ± 0.03 1 0.02 ± 0.02 1 .72
↵a P value was computed using paired t tests; No. indicates number of spectra in which the metabolite was fitted according to defined criteria. Errors are provided as standard error of the mean. Data are means unless otherwise indicated.
↵b P ≤ .008 (Bonferroni-adjusted threshold).
↵c P ≤ .05.

	Baseline (IU)	No.	Week 8 (IU)	No.	P Value
Ace
Contralateral brain	0.04 ± 0.01	5	0.16 ± 0.04	9	.004^{^b}
Lesion	0.06 ± 0.03	4	0.27 ± 0.06	9	.005^{^b}
bHB
Contralateral brain	0.09 ± 0.06	2	0.28 ± 0.08	6	.12
Lesion	0.07 ± 0.07	1	0.79 ± 0.32	5	.046^{^c}
AcAc
Contralateral brain	0.07 ± 0.04	3	0.06 ± 0.03	3	.76
Lesion	0.03 ± 0.03	1	0.02 ± 0.02	1	.72