1naresh

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            [service-id] => ajnr-ac.highwire.org
            [access-type] => Controlled
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1nareshArray
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Demographics and clinical information
Whole Sample Healthy Controls (n = 80) EMCI (n = 79) LMCI (n = 77) AD (n = 79) P
Age (mean) (yr) 75.2 ± 6.4 70.2 ± 7.7 72.3 ± 7.2 75.0 ± 7.5 <.001^{^a}
Female (No.) (%) 41 (51.3) 36 (45.6) 32 (41.6) 36 (45.6) .680
Education (mean) (yr) 16.4 ± 2.3 15.9 ± 2.7 16.5 ± 2.7 15.3 ± 3.1 .022^{^a}
ADAS-cog score (mean) 9.7 ± 4.3 11.9 ± 5.4 18.3 ± 6.2 30.4 ± 6.9 <.001^{^a}
CSF amyloid subsample (n = 53) (n = 68) (n = 54) (n = 47) 
 CSF Aβ-42 (ng/L) (mean) 192.5 ± 56.3 193.5 ± 50 166.6 ± 52.3 137.4 ± 32 <.001^{^a}
 Positive CSF Aβ-42 status (No.) (%) 26 (49.1) 25 (36.8) 36 (66.7) 45 (95.7) <.001^{^a}
CSF tau subsample (n = 31) (n = 68) (n = 48) (n = 20) 
 CSF P-tau (pg/mL) (mean) 38.9 ± 28.8 35.1 ± 21.7 44.1 ± 21.0 58.1 ± 26.2 .002^{^a}
 Positive CSF P-tau status (No.) (%) 22 (71.0) 42 (61.8) 41 (85.4) 19 (95.0) .004^{^a}
APOE subsample (n = 78) (n = 75) (n = 74) (n = 77) 
 APOE-4 carriers (No.) (%) 25 (32.1) 31 (41.3) 37 (50.0) 50 (64.9) <.001^{^a}
↵a Significant.