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Table 2: Global differences in the network properties between the patients with CLN3 and the control subjects, with age and sex used as covariates
Network Property CLN3^a Control Subjects^a P
First Acquisition Second Acquisition CLN3 First Acquisition vs. Control Subjects CLN3 Second Acquisition vs. Control Subjects
Betweenness centrality 288 ± 22 294 ± 17 278 ± 11 .084 .008
Characteristic path length 0.118 ± 0.062 0.130 ± 0.073 0.074 ± 0.014 .003^{^b} .003^{^b}
Clustering coefficient 5.27 ± 1.57 5.32 ± 2.12 6.45 ± 0.77 .011 .017
Degree 25.9 ± 4.6 25.3 ± 5.0 29.5 ± 1.79 .003^{^b} .002^{^b}
Global efficiency 22.6 ± 8.6 22.8 ± 11.6 28.5 ± 4.5 .014 .030
Small-worldness 5.03 ± 0.85 5.24 ± 1.19 5.78 ± 0.80 .009 .126
Strength 511 ± 191 506 ± 255 645 ± 105 .012 .020
a Data are mean± standard deviation.
↵b Indicates significant differences after the Bonferroni correction for multiple comparisons.