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Table 2: 
Significant variables by univariate Cox proportional hazards model analysis of pharmacokinetic parameters
Hazard Ratio (95% CI)aP Value
Baseline first quartile Ktrans1.51 (1.08–2.12).016
Baseline median Ktrans1.26 (1.01–1.57).038
Posttreatment median Ktrans1.22 (1.03–1.45).024
  • ↵a Hazard ratios for Ktrans are adjusted for a unit change of 0.001 min−1.