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Table 1: Demographic and clinical characteristics (N =  29)
Patient Characteristics Results
Sex, n (%) 
 Males 17 (58.6)
 Females 12 (41.6)
Age, n (%) 
 <18 y 15 (51.7)
 ≥18 y 14 (48.3)
Age at first event^a, median (IQR), y −12 (6–36)
Initial clinical presentation, n (%) 
 Ischemic stroke 10 (34.5)
 Intracerebral bleed 5 (17.2)
 TIA 7 (24.2)
 Syncope 1 (3.4)
 Seizure 6 (20.7)
Recurrent events, n (%) 22 (75.9)
 Ischemic stroke 10 (34.5)
 Intracranial bleed (intraventricular hemorrhage) 2 (6.9)
Positive family history of MMD, n (%) 2 (6.9)
NIHSS on admission, median (IQR) 1 (0–3)
mRS on admission, median (IQR) 1 (0–3)
Note:–IQR indicates interquartile range; mRS, modified Rankin scale.
↵a The mean ± SD interval between the first symptom and HRVWI was 64.7 ± 80.7 months.

Patient Characteristics	Results
Sex, n (%)
Males	17 (58.6)
Females	12 (41.6)
Age, n (%)
<18 y	15 (51.7)
≥18 y	14 (48.3)
Age at first event^a, median (IQR), y	−12 (6–36)
Initial clinical presentation, n (%)
Ischemic stroke	10 (34.5)
Intracerebral bleed	5 (17.2)
TIA	7 (24.2)
Syncope	1 (3.4)
Seizure	6 (20.7)
Recurrent events, n (%)	22 (75.9)
Ischemic stroke	10 (34.5)
Intracranial bleed (intraventricular hemorrhage)	2 (6.9)
Positive family history of MMD, n (%)	2 (6.9)
NIHSS on admission, median (IQR)	1 (0–3)
mRS on admission, median (IQR)	1 (0–3)