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Table 1: Baseline patient characteristics (n = 50)
Patient Characteristic No. (%) or Median (Range)
No. of MR imaging studies 50 (100)
Sex 
 Male 24 (48)
 Female 26 (52)
Median age at registration (range) (yr) 6 (3.3–17.5)
Molecular subgroups 
 MGMT–/EGFR– 28/48 (58)
 MGMT–/EGFR+ 14/48 (29)
 MGMT +/EGFR– 3/48 (6)
 MGMT +/EGFR+ 3/48 (6)
 Unassigned 2
Mutational status^{^a} 
 Any histone mutation 34/49 (69)
 Wild-type 15/49 (31)
Histone mutation (among patients with any histone mutations)^{^a} 
 H3F3A 23/34 (68)
 HIST1H3B 8/34 (24)
 HIST1H3C 3/34 (9)
Median follow-up time (range) (mo) 10.9 (0.4–33.4)
↵a One patient with both H3F3A and HIST1H3B histone mutations was excluded.

Patient Characteristic	No. (%) or Median (Range)
No. of MR imaging studies	50 (100)
Sex
Male	24 (48)
Female	26 (52)
Median age at registration (range) (yr)	6 (3.3–17.5)
Molecular subgroups
MGMT–/EGFR–	28/48 (58)
MGMT–/EGFR+	14/48 (29)
MGMT +/EGFR–	3/48 (6)
MGMT +/EGFR+	3/48 (6)
Unassigned	2
Mutational status^{^a}
Any histone mutation	34/49 (69)
Wild-type	15/49 (31)
Histone mutation (among patients with any histone mutations)^{^a}
H3F3A	23/34 (68)
HIST1H3B	8/34 (24)
HIST1H3C	3/34 (9)
Median follow-up time (range) (mo)	10.9 (0.4–33.4)