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Table 2: Results of univariate and multivariate logistic regression analysis of clinical parameters and poor outcome (mRS 3–6) at 90 days^{^a}
Variable Univariate Multivariate
OR 95% CI P Value OR 95% CI P Value
Age 1.03 1.01–1.05 <.001 1.03 1.01–1.06 .016
NIHSS score 1.10 1.05–1.15 <.001 1.10 1.04–1.16 .001
tPA 0.66 0.42–1.03 .067 0.75 0.42–1.37 .354
Medical history
 Hypertension 1.60 0.96–2.68 .071 1.44 0.74–2.80 .283
 Diabetes mellitus 1.82 1.09–3.04 .021 1.96 1.05–3.65 .034
 Hyperlipidemia 1.47 0.93–2.31 .099 1.23 0.67–2.26 .502
 Atrial fibrillation 1.91 1.18–3.10 .008 1.46 0.78–2.76 .239
 Smoking 0.64 0.41–1.01 .051 0.75 0.42–1.32 .319
Procedural timing
 OTE >6 hr^b 1.37 0.82–2.26 .226 2.20 1.11–4.36 .024
 Procedure <30 min 0.75 0.44–1.26 .272 Ref 
 Procedure 30–60 min 0.61 0.37–0.97 .038 0.58 0.27–1.25 .163
 Procedure >60 min 2.01 1.26–3.21 .003 1.32 0.57–2.08 .515
mTICI scale
 mTICI ≤2a 4.85 2.37–9.93 <.001 Ref 
 mTICI 2b 1.74 0.99–3.02 .050 0.52 0.20–1.33 .169
 mTICI 2c 0.39 0.21–0.69 .001 0.11 0.04–0.28 <.001
 mTICI 3 0.50 0.31–0.79 .003 0.15 0.06–0.38 <.001
Procedural sedation
 Moderate sedation 0.58 0.37–0.92 .019 Ref 
 General anesthesia 1.72 1.09–2.72 .019 1.46 0.80–2.65 .213
Thrombectomy passes
 1 Pass 0.53 0.33–0.84 .007 Ref 
 2 Passes^{^b} 1.05 0.65–1.69 .834 1.40 0.70–2.79 .343
 ≥3 Passes 1.93 1.16–3.19 .011 1.62 0.72–3.67 .244
ICH 2.26 1.18–4.35 .014 3.48 1.55–7.82 .003
Note:—Ref indicates reference.
↵a P < .05 considered statistically significant; area under the curve  = 0.820 for final logistic regression model.
↵b Not statistically significant on univariate analysis but included in final model due to clinical relevance.