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Table 5: 
Predictive performance of clinical and image-based featuresa
Positive PathologyPositive Pathology and/or Microbiology
AUCSensitivitySpecificityAUCSensitivitySpecificity
CRP, ESR, and fever0.7268.267.00.6860.564.5
CRP, ESR, fever, and epidural enhancement (observer 1)0.8783.179.80.7668.475.6
CRP, ESR, fever, and epidural enhancement (observer 2)0.7675.066.50.7359.676.2
CRP, ESR, fever, and epidural enhancement (observer 3)0.7977.270.10.7869.375.8
CRP, ESR, fever, and epidural enhancement (majority consensus)0.8078.375.60.7977.474.6
  • ↵a Logistic regression with backward stepwise selection was used to find the optimal combination of clinical and imaging features for 3 independent observers with majority consensus among the observers.