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The correlation between Piezo1 expression and clinicopathologic characteristics in 64 patients with glioblastomas
Characteristics Cases (No.) Expression of Piezo1 P Value
Low^{^a} (No.) High^{^b} (No.)
Cases (No.) 20 44 –
Age (yr) 
 60 or older 12 4 8 .86
 Younger than 60 52 16 36
Sex 
 Male 36 12 24 .68
 Female 28 8 20
Peritumoral brain edema 
 No edema 0 0 0 .00
 Mild edema 9 9 0
 Moderate edema 16 5 11
 Severe edema 39 6 33
Ki-67 index 
 ≥40% 42 10 32 .08
 <40% 22 10 12
IDH1 mutation 
 No 50 16 34 .54
 Yes 14 4 10
p53 status 
 Negative 27 7 20 .43
 Positive 37 13 24
Note:—–indicates not applicable.
↵a “Low” means low Piezo1 expression.
↵b “High” means high Piezo1 expression.

Characteristics	Cases (No.)	Expression of Piezo1		P Value
Characteristics	Cases (No.)	Low^{^a} (No.)	High^{^b} (No.)	P Value
Cases (No.)		20	44	–
Age (yr)
60 or older	12	4	8	.86
Younger than 60	52	16	36	.86
Sex
Male	36	12	24	.68
Female	28	8	20	.68
Peritumoral brain edema
No edema	0	0	0	.00
Mild edema	9	9	0
Moderate edema	16	5	11
Severe edema	39	6	33
Ki-67 index
≥40%	42	10	32		.08
<40%	22	10	12		.08
IDH1 mutation
No	50	16	34	.54
Yes	14	4	10	.54
p53 status
Negative	27	7	20	.43
Positive	37	13	24	.43