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Table 1:

Diagnostic accuracy of imaging biomarkers on CTA in determining patients tested for SARS-CoV-2 (n = 106)

Sensitivity (95% CI)Specificity (95% CI)PPV (95% CI)NPV (95% CI)
Presence of GGO75% (56–87)81% (71–88)58% (41–74)90% (79–95)
Focal GGO46% (29–64)90% (81–95)62% (39–81)82% (72–89)
Bilateral GGO57% (37–75)82% (72–89)53% (35–71)84% (73–91)
Peripheral GGO68% (49–82)88% (79–94)68% (48–83)88% (79–94)
COVID-19-typical/in-determinatea64% (46–79)92% (84–94)77% (50–92)88% (74–95)
  • Note:—PPV indicates positive predictive value; NPV, negative predictive value.

  • a COVID-19-typical alone gave a low sensitivity (36%) and was excluded from further analysis. COVID-19 CT imaging definitions are listed in On-line Table 1.