1naresh
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Variable RCVS (n = 9) No RCVS (n = 17) Pa Age (mean) (yr) 44.9 55.7 .06 Women (%) 8 (88.9) 10 (58.8) .19 Race White (%) 8 (88.9) 12 (70.6) .39 African American (%) 1 (11.1) 2 (11.8) Other (%) 0 (0) 3 (17.7) Medical history Migraine (%) 4 (44.4) 0 (0) .008 Depression/anxiety (%) 8 (88.9) 3 (17.6) .001 Hypertension (%) 2 (22.2) 14 (82.4) .009 Trigger/associated condition 7 (77.8) 2 (11.8) .002 Vasoconstrictive drugs SSRI (%) 6 (66.7) 1 (5.9) .002 Illicit drugs (%) 0 (0) 1 (5.9) .65 Postpartum (%) 2 (22.2) 0 (0) .11 Clinical presentation Thunderclap headache (%) 5 (55.6) 1 (5.9) .01 Other headaches (%) 2 (22.2) 5 (29.4) .54 Focal neurologic signs Hemiparesis/aphasia (%) 5 (55.6) 10 (58.8) .99 Visual symptoms (%) 3 (33.3) 1 (5.9) .10 Seizures (%) 2 (22.0) 1 (5.9) .27 Diagnostic work-up ESR (mean) (mm/h) 22.5 43.9 .31 CRP (mean) (mg/L) 3.0 1.9 .61 Normal CSFb (%) 2/5 (40.0) 4/9 (44.4) .99 Brain biopsy (%) 1 (11.1) 1 (5.9) .58 Abnormal neuroimaging findings (%) Infarct (%) 3 (33.3) 13 (76.5) .046 Multiple (%) 2/3 (66.7) 12/13 (92.3) .35 Borderzone territory (%) 2/3 (66.7) 1/13 (7.7) .08 IPH (%) 0 (0) 4 (23.5) .26 SAH in convexity (%) 5 (55.6) 2 (11.8) .03 CTA/MRA with vasculopathy CTA [n = 14]c (%) 2/5 (40) 5/9 (55.6) .99 MRA [n = 16]c (%) 2/6 (33.3) 10/10 (100) .008 Patients with intracranial vasculopathy on DSA not detected by CTA and/or MRA (n = 26) (%) 6/9 (66.7) 3/17 (17.6) .028 RCVS-2 score of ≥ 5 5 (55.6) 1 (5.9) .01
Note:—CRP indicates C-reactive protein; ESR, erythrocyte sedimentation rate; IPH, intraparenchymal hemorrhage; SSRI, selective serotonin reuptake inhibitor.
↵a P value calculated using a t test, χ2 test, or Fisher test as appropriate.
↵b Normal CSF if <5 cells and <50 mg/dL.
↵c Number of examinations performed including both groups.