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Sample MR imaging protocol for suspected PHACE syndromea
Sequence Feature Evaluated Coronal and axial T2 fat-suppressed head and neck Facial hemangioma, extent of lesion, possible hemangioma in airway Axial DWI brain Acute ischemia Sagittal T1 or spoiled gradient-echo head and neck Midline intracranial structures including pituitary gland, myelination Axial ASL head and neck Cerebral blood flow, hemangioma Axial time-of-flight MRA head and neck Arterial abnormalities Coronal contrast-enhanced dynamic MRA/MRV neck, if needed Arterial abnormalities, including evaluation of the aortic arch Axial contrast-enhanced T1 fat-suppressed head and neck Enhancement pattern Coronal contrast-enhanced T1 fat-suppressed internal auditory canals Hemangioma in the internal auditory canals
↵a Modified from Mamlouk et al13 with permission from Elsevier.