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Detection and segmentation accuracy on the independent test cohort
  Majority Voting Scheme First Fold Second Fold Third Fold Fourth Fold Fifth Fold
Detection 
 Sensitivity 88% 88% 88% 81% 91% 91%
 Precision 74% 49% 35% 40% 41% 51%
 F1 score 0.80 0.63 0.50 0.53 0.57 0.65
 Missed 4 4 4 6 3 3
FPs/scan 0.71 2.1 3.8 2.9 2.9 2.0
Segmentation 
 Dice coefficient 0.75 0.78 0.73 0.73 0.76 0.78
Note:—Missed indicates missed brain metastases in the test cohort; FPs/scan, false-positive lesion findings per patient; Dice coefficient, similarity score reported as median; Majority Voting Scheme, fusion of the 5 deep learning models from the 5-fold cross-validation; First Fold, first deep learning model from the 5-fold cross-validation.

	Majority Voting Scheme	First Fold	Second Fold	Third Fold	Fourth Fold	Fifth Fold
Detection
Sensitivity	88%	88%	88%	81%	91%	91%
Precision	74%	49%	35%	40%	41%	51%
F1 score	0.80	0.63	0.50	0.53	0.57	0.65
Missed	4	4	4	6	3	3
FPs/scan	0.71	2.1	3.8	2.9	2.9	2.0
Segmentation
Dice coefficient	0.75	0.78	0.73	0.73	0.76	0.78