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Clinical and imaging information of patients includeda
All Patients (n = 237)Minimal Reperfusion (n = 52)Major Reperfusion (n = 80)Partial Reperfusion (n = 57)Unknown Reperfusion (n = 48)P Value
Male108 (46)27 (52)39 (49)25 (44)17 (35).3
Age (yr)66 [SD, 16]64 [SD, 16]66 [SD, 16]69 [SD, 14]64 [SD, 17].4
Hypertension159 (67)39 (75)50 (63)39 (68)31 (65).3
Diabetes58 (25)14 (27)18 (23)15 (26)11 (23).8
Dyslipidemia97 (41)24 (46)30 (38)30 (53)13 (28).6
Atrial fibrillation73 (31)12 (23)27 (34)21 (37)13 (28).4
Treatment methods.004
    IV tPA only79 (33)25 (48)18 (22)21 (37)15 (31)
    Direct thrombectomy62 (26)8 (15)29 (36)16 (28)9 (19)
    Bridging therapy77 (32)13 (25)31 (39)16 (28)17 (35)
    No treatment19 (8)6 (12)2 (3)4 (7)7 (15)
Onset-to-treatment time (hr)5.7 (4.7–7.4)5.8 (5.2–6.3)5.8 (4.6–7.8)5.4 (4.6–6.4)5.8 (4.9–7.7).9
Baseline DWI lesion volume (mL)22 (8–57)20 (6–63)17 (6–43)31 (16–83)31 (13–61).01
Baseline Tmax lesion volume (mL)115 (68–173)98 (48–158)115 (71–160)126 (66–188)123 (80–171).3
PWI/DWI mismatch ratiob3.8 (1.9–8.6)2.9 (1.4–6.8)5.4 (2.3–13.9)3.3 (2.0–5.8)3.2 (1.6–6.6).006
Baseline NIHSS14 (10–19)13 (8–19)15 (9–19)16 (10–19)14 (11–19).3
Symptomatic hemorrhage27 (11)7 (13)8 (10)8 (14)4 (8).1
Reperfusion rate (%)69 (15–97)0 (0–9)100 (92–100)55 (37–68)NA<.001
Final infarct volume (mL)49 (14–108)59 (28–204)19 (8–62)77 (33–149)57 (22–112)<.001
90-day mRS3 (1–4)3 (2–4)2 (1–3)4 (2–5)3 (1–4)<.001
  • Note:—NA indicates not applicable.
  • ↵a Data are expressed as No. (%), median (IQR), or mean [SD].
  • ↵b The upper limit of the mismatch ratio was set to 20 if a small or no ischemic core lesion presented at baseline.