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Table 4: Effect of processing on the CNR of optic nerves relative to ipsilateral normal-appearing white matter in cases with optic neuritis and controls with normal optic nerve function
Sequence Type Median CNR (25th–75th Percentiles) for Optic Nerves with Optic Neuritis P Value Median CNR (25th–75th Percentiles) for Normal Optic Nerves P Value
FL before processing −1.05 (−46.7−81.3) <.001 −12.7 (−86.9−106.9) .25
FL after processing 54.4 (−46.7−795.6) −12.7 (−86.9−137.9)
CCE before processing 9.8 (−181.8−129.2) <.001 2.6 (−83.2–179.1) .50
CCE after processing 6.2 (−181.8−238.1) −0.37 (−83.2−66.8)
ACE before processing 11.8 (−29.6−267.8) .03 −14.3 (−63.1−2.5) .27
ACE after processing 93.9 (−29.6−543.3) −14.3 (−63.1−2.5)
Note:—FL indicates FLAIR; CCE, coronal CE-T1WI; ACE, axial CE-T1WI.