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Table 2: Logistic regression analysis for the predictors of β-amyloid positivity
Univariable Multivariable
OR (95% CI) P Value OR (95% CI) P Value
Age (yr) 1.051 (1.012–1.092) .010 1.050 (1.004–1.098) .034
Sex 
 Female Reference group 
 Male 1.435 (0.729–2.823) .296 1.561 (0.699–3.489) .278
Hypertension (present) 1.475 (0.757–2.875) .254 
Diabetes (present) 1.495 (0.627–3.564) .364 
Hyperlipidemia (present) 1.074 (0.416–2.774) .883 
Previous stroke (present) 0.470 (0.131–1.681) .245 
APOE ε4 allele (present) 3.526 (1.630–7.627) .001 4.583 (1.945–10.796) <.001
High degree of MR imaging–visible PVS-CS (score, ≥3) 2.966 (1.503–5.851) .002 2.307 (1.036–5.136) .041
High degree of MR imaging–visible PVS-BG (score, ≥3) 1.034 (0.429–2.492) .940 
WMH (present) 2.321 (1.188–4.533) .014 
Lacunes (for 1 number higher) 0.937 (0.726–1.209) .618 
cSS (present) 5.577 (0.654–47.565) .116 
Lobar CMB (present) 1.100 (0.934–1.295) .253 
Deep CMB (present) 0.688 (0.428–1.108) .124 
Note:—CMB indicates cerebral microbleed; cSS, cortical superficial siderosis; MRI-visible PVS-BG, enlarged perivascular space in the basal ganglia; MRI-visible PVS-CS, enlarged perivascular space in the semi ovale.