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Table 1: 
Baseline characteristics of the groups positive and negative for brain β-amyloid
Amyloid-NegativeAmyloid-PositiveP Value
(No.) (%)67 (46.5%)77 (53.5%)
Age (mean) (SD) (yr)71.3 (10.6)75.4 (7.6).010
Female sex (No.) (%)44 (65.7%)44 (57.1%).297
Hypertension (No.) (%)25 (37.3%)36 (46.8%).254
Diabetes mellitus (No.) (%)10 (14.9%)16 (20.8%).364
Hyperlipidemia (No.) (%)9 (13.4%)11 (14.3%).883
Previous stroke (No.) (%)7 (10.4%)4 (5.2%).238
APOE ε4 presence (No.) (%)13 (19.4%)33 (42.9%).001
High degree of MR imaging–visible PVS-CS (No.) (%)24 (35.8%)48 (62.3%).002
High degree of MR imaging–visible PVS-BG (No.) (%)11 (16.4%)13 (16.9%).297
AD (No.) (%)19 (28.4%)47 (61.0%)<.001
MMSE (median) (IQR)26 (23–28)24 (20–26)<.001
CDR (median) (IQR)0.5 (0.5–0.5)0.5 (0.5–1.0).019
CDR-SB (median) (IQR)1.5 (0.5–3.0)3.0 (1.5–4.5)<.001
Lacunes (median) (IQR)0 (0–0)0 (0–0).778
cSS present (No.) (%)1 (1.5%)6 (7.8%).081
Lobar CMB (median) (IQR)0 (0–0)0 (0–1).117
Deep CMB (median) (IQR)0 (0–0)0 (0–0).160
WMH presence (No.) (%)27 (40.3%)47 (61.0%).013
  • Note:—IQR indicates interquartile range; PVS-BG, perivascular space in the basal ganglia; CMB, cerebral microbleed; CDR, Clinical Dementia Rating Scale; CDR-SB, Clinical Dementia Rating Scale–Sum of Boxes; cSS, cortical superficial siderosis.