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Summary CoW measurements in healthy children versus adults
 Children (0–18 years of age)Adults (19–74 years of age)
No. of participants2343
Age (range) (yr)9.5 (4–18)40.7 (19–74)
Sex (female, male)11, 1221, 22
Excluded data4 of 231 of 43
TOF-MRA CoW-area (mean) (mm2)27.7 (SD, 7.9)17.8 (SD, 4.2)
TOF-MRA CoW-di (mean)0.48 (SD, 0.30)0.84 (SD, 0.49)
T2-SPACE CoW-area (mean) (mm2)16.6 (SD, 4.1)14.2 (SD, 4.0)
T2-SPACE CoW-di (mean)0.68 (SD, 0.29)0.93 (SD, 0.49)
Nonvisualized segments5/133 (3.8%)31/294 (10.5%)
Whole-brain CBF (mean) (L/min)1.10 (SD, 0.24)0.69 (SD, 0.21)