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Table 2: 
Frequency of morphologic anomalies in the 2 groups
CharacteristicControls (n = 53)22q11.2DS (n = 75)P Valuea (FDR-Adjusted)
Any morphologic finding0 (0%)48 (64%)<.001
Heterotopia
 Any localization0 (0%)34 (45%)<.001
 PNH0 (0%)10 (13%).007
 Heterotopia in the WM0 (0%)29 (39%)<.001
CSP and/or CV0 (0%)20 (27%)<.001
 Isolated CSP0 (0%)1 (1.3%)>.9
 CSP/CV0 (0%)19 (25%)<.001
Cysts0 (0%)10 (13%).007
Polymicrogyria0 (0%)3 (4.0%).30
  • Note:—FDR indicates false discovery rate.
  • ↵a Fisher exact test.