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Table 2: Clinical and imaging predictors associated with TTP in PCNSL
Variable Hazard Ratio 95% CI P Value
Age 0.98 0.94–1.03 .55
Atypical finding^{^a} 4.41 1.32–14.71 .016
CSF-total protein 1.00 0.99–1.00 .70
ECOG 
 2 (reference) 
 3 or 4 5.82 1.07–31.66 .04
Serum LDH level 1.01 1.00–1.02 .013
Deep location^{^b} 1.75 0.33–9.08 .50
↵a Atypical findings: presence of hemorrhage or necrosis.
↵b Deep location: thalamus, basal ganglia, corpus callosum, periventricular area, cerebellum.

Variable	Hazard Ratio	95% CI	P Value
Age	0.98	0.94–1.03	.55
Atypical finding^{^a}	4.41	1.32–14.71	.016
CSF-total protein	1.00	0.99–1.00	.70
ECOG
2 (reference)
3 or 4	5.82	1.07–31.66	.04
Serum LDH level	1.01	1.00–1.02	.013
Deep location^{^b}	1.75	0.33–9.08	.50