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Table 2: Results from the Spearman rank correlation analysis for collateral score as a function of perfusion parameters (ρ [95% CI] and P value) and from ROC analysis for the identification of good collateral status^{^a}
Perfusion Parameter ρ (95% CI) P Value AUC (95% CI) Cutoff Value Sensitivity Specificity Accuracy
Tmax >6 sec (mL) −0.50 (−0.61 to −0.39) <.001 0.75 (0.68–0.81)^{^b} 124 mL 56% 82% 69%
Tmax >8 sec (mL) −0.54 (−0.64 to −0.43) <.001 0.77 (0.71–0.83)^{^b} 74 mL 68% 76% 72%
Tmax >10 sec (mL) −0.50 (−0.60 to−0.39) <.001 0.77 (0.71–0.83)^{^b} 53 mL 64% 80% 72%
rCBF < 30% (mL) −0.61 (−0.71 to −0.52) <.001 0.81 (0.75–0.87) 14 mL 72% 82% 77%
rCBF < 34% (mL) −0.64 (−0.73 to −0–55) <.001 0.83 (0.77–0.88) 25 mL 67% 87% 77%
rCBF < 38% (mL) −0.66 (−0.74 to −0.57) <.001 0.83 (0.78–0.89) 27 mL 75% 80% 77%
CBV-index +0.51 (0.40–0.63) <.001 0.76 (0.69–0.81)^{^b} 0.8 60% 78% 69%
HIR −0.49 (−0.60−0.37) <.001 0.73 (0.66–0.79)^{^b} 0.4 75% 62% 65%
↵a Overall, the volume with an rCBF < 38% performed best. Optimal cutoff values to identify good collateral supply were estimated according to the Youden index.
↵b Significant differences in AUC compared with the AUC for the volume with rCBF < 38%.