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Patient demographics of spinal CSF leaks
Demographics All Patients Type 1 Type 2 Type 3 P Value^a
No. of leaks 65 25 (39%) 4 (6%) 36 (55%) 
Age at symptoms onset (yr) <.00001
 Mean (SD) 52.4 (13.1) 44.5 (10.3) 45.5 (8.1) 58.8 (11.9) 
 95% CI 49.3–55.6 40.4–48.5 37.6–53.4 54.9–62.6 
 Range 28–91 28–68 34–53 39–91 
Sex (No.) .81
 Female 37 14 4 19 
 Male 28 11 0 17 
BMI .015
 Mean (SD) 26.0 (4.5) 24.3 (3.1) 27.5 (7.9) 27.0 (4.7) 
 95% CI 24.9–27.1 23.1–25.5 19.7–35.3 25.4–28.5 
 Range 16–39 18–31 21–39 16–39 
Leak location (No.) <.0002
 Cervical 2 2 0 0 
 Upper thoracic (T1–T6) 31 18 0 13 
 Lower thoracic (T7–T12) 29 5 4 20 
 Lumbar 3 0 0 3 
Bern SIH score .44
 Mean (SD) 5.7 (2.4) 5.4 (2.0) 5.8 (3.3) 5.9 (2.6) 
 Range 0–9 0–8 1–8 0–9 
↵a P values were compared between type 1 and 3 groups.

Demographics	All Patients	Type 1	Type 2	Type 3	P Value^a
No. of leaks	65	25 (39%)	4 (6%)	36 (55%)
Age at symptoms onset (yr)					<.00001
Mean (SD)	52.4 (13.1)	44.5 (10.3)	45.5 (8.1)	58.8 (11.9)
95% CI	49.3–55.6	40.4–48.5	37.6–53.4	54.9–62.6
Range	28–91	28–68	34–53	39–91
Sex (No.)					.81
Female	37	14	4	19
Male	28	11	0	17
BMI					.015
Mean (SD)	26.0 (4.5)	24.3 (3.1)	27.5 (7.9)	27.0 (4.7)
95% CI	24.9–27.1	23.1–25.5	19.7–35.3	25.4–28.5
Range	16–39	18–31	21–39	16–39
Leak location (No.)					<.0002
Cervical	2	2	0	0
Upper thoracic (T1–T6)	31	18	0	13
Lower thoracic (T7–T12)	29	5	4	20
Lumbar	3	0	0	3
Bern SIH score					.44
Mean (SD)	5.7 (2.4)	5.4 (2.0)	5.8 (3.3)	5.9 (2.6)
Range	0–9	0–8	1–8	0–9