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Table 4: Diagnostic performance of DCE-MR imaging parameters for each tumor comparison^{^a}
Parameters Chondrosarcoma vs Chordoma Chondrosarcoma vs Metastasis Chordoma vs Metastasis
nADCmean Vp nADCmean Vp K^trans (minute⁻¹) Vp K^trans (minute⁻¹)
Cutoff 1.99 0.03 2.09 0.06 0.12 0.09 0.30
Sensitivity 1.0 (0.68–1) 0.93 (0.66–0.99) 0.93 (0.76–0.99) 0.93 (0.78–0.99) 0.93 (0.78–0.99) 0.80 (0.61–0.92) 0.60 (0.41–0.77)
Specificity 0.86 (0.57–0.98) 0.71 (0.42–0.92) 0.87 (0.60–0.98) 0.93 (0.66–0.9) 0.71 (0.42–0.92) 0.93 (0.66–1) 1.0 (0.68–1)
PPV 0.88 (0.62–0.98) 0.77 (0.50–0.93) 0.93 (0.76–0.99) 0.97 (0.82–1) 0.88 (0.71–0.97) 0.96 (0.80–1) 1.0 (0.74–1)
NPV 1.0 (0.64–1) 0.91 (0.59–0.99) 0.87 (0.60–0.98) 0.87 (0.60–0.98) 0.83 (0.52–0.98) 0.68 (0.43–0.87) 0.54 (0.33–0.73)
Accuracy 0.93 (0.78–0.99) 0.82 (0.63–0.94) 0.91 (0.77–0.97) 0.93 (0.81–0.99) 0.86 (0.73–0.95) 0.84 (0.70–0.93) 0.73 (0.57–0.85)
AUC 0.96 (0.90–1) 0.86 (0.72–1) 0.95 (0.88–1) 0.99 (0.96–1) 0.82 (0.67–0.98) 0.92 (0.84– 1) 0.82 (0.70–0.95)
Note:—PPV indicates positive predictive value; NPV, negative predictive value.
↵a Numbers in parentheses represent 95% CIs.